Deltamethrin (Standard)

• CAS Number:

  52918-63-5

• UNSPSC Description:

  Deltamethrin (Standard) is the analytical standard of Deltamethrin. This product is intended for research and analytical applications. Deltamethrin (Decamethrin) is an orally active synthetic pyrethroid insecticide. Deltamethrin induces oxidative stress and results in inflammation and apoptosis via inhibiting Nrf2/HO-1 pathway. Deltamethrin has an anticancer effect by inducing apoptosis. Deltamethrin can be used extensively in pest control[1][2][3][4][5][6].

• Target Antigen:

  Apoptosis; Bcl-2 Family; Calcium Channel; Caspase; Endogenous Metabolite; Interleukin Related; NF-κB

• Type:

  Reference Standards

• Related Pathways:

  Apoptosis;Immunology/Inflammation;Membrane Transporter/Ion Channel;Metabolic Enzyme/Protease;Neuronal Signaling;NF-κB

• Field of Research:

  Cancer; Inflammation/Immunology; Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/deltamethrin-standard.html

• Smiles:

  O=C([C@H]1C(C)(C)[C@H]1/C=C(Br)\Br)O[C@H](C#N)C2=CC=CC(OC3=CC=CC=C3)=C2

• Molecular Weight:

  505.20

• References & Citations:

  [1]Lu Q, et al. Deltamethrin toxicity: A review of oxidative stress and metabolism [J]. Environmental research, 2019, 170: 260-281.|[2]Chi C C, et al. Effect of the pesticide, deltamethrin, on Ca2+ signaling and apoptosis in OC2 human oral cancer cells [J]. Drug and Chemical Toxicology, 2014, 37(1): 25-31.|[3]Kumar A, et al. Deltamethrin induced an apoptogenic signalling pathway in murine thymocytes: exploring the molecular mechanism [J]. Journal of Applied Toxicology, 2014, 34(12): 1303-1310.|[4]Rehman H, et al. The modulatory effect of deltamethrin on antioxidants in mice [J]. Clinica Chimica Acta, 2006, 369(1): 61-65.|[5]Hossain M M, et al. Neuromechanical effects of pyrethroids, allethrin, cyhalothrin and deltamethrin on the cholinergic processes in rat brain [J]. Life sciences, 2005, 77(7): 795-807|[6]Yang X, et al. The heart as a target for deltamethrin toxicity: Inhibition of Nrf2/HO-1 pathway induces oxidative stress and results in inflammation and apoptosis [J]. Chemosphere, 2022, 300: 134479.

• Shipping Conditions:

  Room temperature