USP1-IN-7

• CAS Number:

  3033480-42-8

• UNSPSC Description:

  USP1-IN-7 (Compound 3) is an inhibitor for ubiquitin specific peptidase 1 (USP1) and its cofactor UAF1, with IC50 ≤50 nM. USP1-IN-7 inhibits proliferation of MDA-MB-436 with IC50 ≤50 nM[1].

• Target Antigen:

  Deubiquitinase

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/usp1-in-7.html

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  CN(C1=CN=C(C(F)=C1N2CC3=CC=C(C4=NC(C(F)(F)F)=CN4C)C=C3)C5=C(OC)N=CN=C5C6CC6)C2=O

• Molecular Weight:

  553.51

• References & Citations:

  [1]Liu BM, et al., Carbonyl fused heterocyclic derivative used as ubiquitin-specific protease inhibitor. WO2024061213A1.

• Shipping Conditions:

  Room Temperature

• Clinical Information:

  No Development Reported