VU0155041

VU0155041

• CAS Number: 1093757-42-6
• UNSPSC Description: VU0155041 is a potent, selective positive allosteric modulator (PAM) of mGluR4, with EC50s of 798 nM and 693 nM for human and rat mGluR4, respectively. VU0155041 has potential for the research of Parkinson's disease (PD)[1].
• Target Antigen: mGluR
• Type: Reference compound
• Related Pathways: GPCR/G Protein;Neuronal Signaling
• Applications: Neuroscience-Neurodegeneration
• Field of Research: Neurological Disease
• Assay Protocol: https://www.medchemexpress.com/vu0155041.html
• Solubility: DMSO : 100 mg/mL (ultrasonic)
• Smiles: O=C([C@H](CCCC1)[C@H]1C(O)=O)NC2=CC(Cl)=CC(Cl)=C2
• Molecular Weight: 316.18
• References & Citations: [1]Niswender CM, et, al. Discovery, characterization, and antiparkinsonian effect of novel positive allosteric modulators of metabotropic glutamate receptor 4. Mol Pharmacol. 2008 Nov; 74(5): 1345-58.
• Shipping Conditions: Room Temperature
• Clinical Information: No Development Reported