2-Methoxy-5-acetoxy-fruranogermacr-1(10)-en-6-one

• CAS Number:

  1809980-25-3

• UNSPSC Description:

  2-Methoxy-5-acetoxy-fruranogermacr-1(10)-en-6-one is a natural product found in the leaves and stem bark of M. glabra. 2-Methoxy-5-acetoxy-fruranogermacr-1(10)-en-6-one displays binding affinities with dipeptidyl peptidase-4 (DPP-4) and α-Amylase. 2-Methoxy-5-acetoxy-fruranogermacr-1(10)-en-6-one has potential antidiabetic activities[1].

• Target Antigen:

  Dipeptidyl Peptidase

• Type:

  Natural Products

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/2-methoxy-5-acetoxy-fruranogermacr-1-10-en-6-one.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C([C@@H]([C@@H](C1)C)OC(C)=O)C(C(C)=CO2)=C2C/C(C)=C/[C@@H]1OC

• Molecular Weight:

  320.38

• References & Citations:

  [1]Alexandra Quek, et al. Identification of Dipeptidyl Peptidase-4 and α-Amylase Inhibitors from Melicope glabra (Blume) T. G. Hartley (Rutaceae) Using Liquid Chromatography Tandem Mass Spectrometry, In Vitro and In Silico Methods. Molecules. 2021 Jan; 26(1): 1.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported