Prostate Specific Antigen Recombinant Rabbit Monoclonal Antibody [SD07-45]

• Description:

  Prostate specific antigen (PSA), also designated γ-seminoprotein, seminin, p30 antigen, semenogelase, and kallikrein 3 (KLK3), was first identified as a glycoprotein in human seminal plasma. PSA was determined by sequence similarity to be a member of the kallikrein subfamily of trypsin proteases. PSA is a serine protease that hydrolyzes the major human seminal protein, the seminal plasma mobility inhibitor precursor, or semenogelin I (SPMIP or SgI), which leads to semen liquification. PSA production and expression are highest in normal, benign hyperplastic and cancerous tissues of the prostate, although PSA has also been detected in accessory male sex glands and in breast cancer. PSA has been identified as an aid in the early detection of prostate cancer and is a commonly used tumor marker.

• Product Name Alternative:

  antigen, prostate-specific antibody APS antibody Gamma seminoprotein antibody Gamma-seminoprotein antibody hK3 antibody Kallikrein 3 antibody Kallikrein related peptidase 3 antibody Kallikrein-3 antibody KLK 3 antibody KLK2A1 antibody Klk3 antibody KLK3_HUMAN antibody P-30 antigen antibody P30 antigen antibody Prostate-specific antigen antibody Psa antibody Semenogelase antibody Seminin antibody

• Abbreviation:

  PSA, Seminin, KLK3

• CAS Number:

  9000-83-3

• Swiss Prot:

  P07288 Human

• Cellular Locus:

  Secreted.

• Host:

  Rabbit

• Species Reactivity:

  Human

• Immunogen:

  Recombinant protein within human Prostate Specific Antigen aa 198-261/261.

• Isotype:

  IgG

• Conjugation:

  Non-conjugated

• Type:

  Recombinant Rabbit monoclonal Antibody

• Applications:

  WB, IF-Cell, IF-Tissue, IHC-P

• Positive Control:

  PC-3M, human prostate tissue, human prostate carcinoma tissue.

• Concentration:

  1 mg/mL

• Dilution:

  WB: 1:1,000;IF-Cell: 1:50-1:200;IF-Tissue: 1:50-1:200;IHC-P: 1:50-1:200

• Purity:

  Protein A affinity purified.

• Form:

  Liquid

• Buffer:

  1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

• Molecular Weight:

  34 kDa

• Storage Conditions:

  Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

• Recombinant Antibody:

  Yes