Hsp110-STAT3 interaction-IN-2

• UNSPSC Description:

  Hsp110-STAT3 interaction-IN-2 (compound 10b) is a Hsp110-STAT3 interaction disruptor. Hsp110-STAT3 interaction-IN-2 can be used in pulmonary arterial hypertension (PAH) related research[1].

• Target Antigen:

  HSP; STAT

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage;JAK/STAT Signaling;Metabolic Enzyme/Protease;Stem Cell/Wnt

• Field of Research:

  Cardiovascular Disease

• Assay Protocol:

  https://www.medchemexpress.com/hsp110-stat3-interaction-in-2.html

• Smiles:

  OC1=CC=CC(C2=NC(C3=C(OCC4=CC=CC(C)=C4)N=C(N(C)N=C5C(F)(F)F)C5=C3)=NO2)=C1

• Molecular Weight:

  481.43

• References & Citations:

  [1]Li M, et al. Design, synthesis and optimization of pyrazolo[3,4-b] pyridine derivatives as Hsp110-STAT3 interaction disruptors for the treatment of pulmonary arterial hypertension. Bioorg Chem. 2024 Oct 14;153:107888.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported