Deoxyandrographolide

• CAS Number:

  79233-15-1

• UNSPSC Description:

  Deoxyandrographolide suppresses LPS induced increase in mRNA levels of iNOS as well as production of proinflammatory mediators TNF-α and IL-6. Deoxyandrographolide potentiates NGF-induced neurite outgrowth[1].

• Target Antigen:

  Interleukin Related

• Type:

  Natural Products

• Related Pathways:

  Immunology/Inflammation

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology; Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/Deoxyandrographolide.html

• Purity:

  99.87

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  C[C@@](C(CCC1=CCOC1=O)=C(C)CC2)(CC[C@H]3O)[C@@]2([H])[C@]3(C)CO

• Molecular Weight:

  334.45

• References & Citations:

  [1]Xu Y, et al. Synthesis of andrographolide analogues and their neuroprotection and neurite outgrowth-promoting activities. Bioorg Med Chem. 2019;27(11):2209-2219.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, protect from light)

• Clinical Information:

  No Development Reported