GLP-1R modulator C5

• CAS Number:

  421578-93-0

• UNSPSC Description:

  GLP-1R modulator C5 is an allosteric modulator enhancing GLP-1 binding to GLP-1R via a transmembrane site (EC50 1.59 ± 0.53 μM).

• Target Antigen:

  GCGR

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/glp-1r-modulator-c5.html

• Solubility:

  DMSO : 50 mg/mL (ultrasonic)

• Smiles:

  O=C(C1=CC=CC=C1)CC2(C(N(C3=CC=CC=C32)CCC4=CC=CC=C4)=O)O

• Molecular Weight:

  371.43

• References & Citations:

  [1]Wang J, et al. Allosteric Modulators Enhancing GLP-1 Binding to GLP-1R via a Transmembrane Site. ACS Chem Biol. 2021 Nov 19;16(11):2444-2452.

• Shipping Conditions:

  Room Temperature

• Clinical Information:

  No Development Reported