B7/CD28 interaction inhibitor 1
CAT:
804-HY-102090-03
Size:
10 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
B7/CD28 interaction inhibitor 1
- CAS Number: 635324-72-0
- UNSPSC Description: B7/CD28 interaction inhibitor 1 (copmound 6b) is a potent B7.1-CD28 interaction inhibitor with an IC50 of 50 nM[1].
- Target Antigen: CD28
- Type: Reference compound
- Related Pathways: Immunology/Inflammation
- Applications: COVID-19-anti-virus
- Field of Research: Inflammation/Immunology
- Assay Protocol: https://www.medchemexpress.com/ctla-4-inhibitor-1.html
- Purity: 99.47
- Solubility: DMSO : 62.5 mg/mL (ultrasonic)
- Smiles: O=C1N(C2=CC=C(F)C=C2)NC3=C4C(N(C)N=C4)=NC(C5=CC=CC(C(F)(F)F)=C5)=C31
- Molecular Weight: 427.35
- References & Citations: [1]Green NJ, et al. Structure-activity studies of a series of dipyrazolo[3,4-b:3',4'-d]pyridin-3-ones binding to the immune regulatory protein B7.1. Bioorg Med Chem. 2003 Jul 3;11(13):2991-3013.
- Shipping Conditions: Room Temperature
- Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
- Clinical Information: No Development Reported