Anti-CD8B (Cytotoxic / Suppressor T-Cell Marker)(CBB/1595), CF640R conjugate

• Description:

  The CD8 beta chain associates with the CD8 alpha chain to form the CD8 alpha/beta heterodimer expressed on the surface of a majority of thymocytes, and on peripheral cytotoxic alpha beta TCR T cells. This monoclonal antibody identifies cytotoxic/suppressor T-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of T-cell mediated killing.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

• Synonyms:

  CD8 antigen 37kDa chain; CD8 antigen; beta chain; CD8 antigen; beta polypeptide 1 (p37); CD8 antigen; beta polypeptide 1; CD8B; LEU2; LYT3; OX 8 membrane antigen; p37; T cell surface glycoprotein CD8 beta chain

• CAS Number:

  9007-83-4

• UNSPSC:

  41116161

• UNSPSC Description:

  Primary and secondary antibodies for multiple methodology immunostaining detection application

• Gene Name:

  CD8B

• Gene ID:

  926

• NCBI Gene ID:

  405667

• UniProt:

  P10966

• Cellular Locus:

  Plasma membrane

• Host:

  Mouse

• Species Reactivity:

  Bovine, Goat, Sheep

• Immunogen:

  Antibody was raised against bovine CD8b.

• Target Antigen:

  CD8b,

• Clonality:

  Monoclonal

• Isotype:

  IgG1 κ

• Clone:

  CBB/1595

• Conjugation:

  CF640R

• Source:

  Animal

• Positive Control:

  HuT78 or hPBL. Tonsil

• Concentration:

  0.1 mg/mL

• Buffer:

  PBS, 0.1% BSA, 0.05% azide

• Molecular Weight:

  32 kDa

• Additionnal Information:

  For coating for ELISA, order Ab without BSA|Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody|Optimal dilution and staining procedure for a specific application should be determined by user|Recommended starting concentrations for titration are 1-2 ug/mL for most applications, or 1 ug/million cells/100 uL for flow cytometry

• Shipping Conditions:

  Room temperature

• Storage Conditions:

  4°C; Protect from light; Stable at room temperature or 37°C (98°F) for 7 days.

• Shelf Life:

  2 years