Anti-CD268 / BAFFR / TNFRSF13C(BAFFR/1557), CF405S conjugate

• Description:

  Defects in TNFRSF13C are the cause of immunodeficiency common variable type 4 (CVID4) ; also called antibody deficiency due to BAFFR defect. CVID4 is a primary immunodeficiency characterized by antibody deficiency, hypogammaglobulinemia, recurrent bacterial infections and an inability to mount an antibody response to antigen. The defect results from a failure of B-cell differentiation and impaired secretion of immunoglobulins; the numbers of circulating B cells is usually in the normal range, but can be low. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

• Synonyms:

  TNFRSF13C; BAFFR; BR3; BAFF receptor; BLyS receptor 3; CD268; CD268 antigen; CVID4; Prolixin; BAFF-R; BROMIX

• CAS Number:

  9007-83-4

• UNSPSC:

  41116161

• UNSPSC Description:

  Primary and secondary antibodies for multiple methodology immunostaining detection application

• Gene Name:

  TNFRSF13C

• Gene ID:

  115650

• NCBI Gene ID:

  344088

• UniProt:

  Q96RJ3

• Cellular Locus:

  Plasma membrane

• Host:

  Mouse

• Species Reactivity:

  Human

• Immunogen:

  Recombinant full-length human CD268 protein

• Target Antigen:

  BAFFR | CD268 | TNFRSF13C

• Clonality:

  Monoclonal

• Isotype:

  IgG1 κ

• Clone:

  BAFFR/1557

• Conjugation:

  CF405S

• Source:

  Animal

• Applications:

  IHC, FFPE (verified)

• Validated Applications:

  IHC, FFPE

• Positive Control:

  Raji cells. Tonsil and lymph node.

• Concentration:

  0.1 mg/mL

• Buffer:

  PBS, 0.1% BSA, 0.05% azide

• Molecular Weight:

  19 kDa (Monomer); 40 kDa (Dimer)

• Shipping Conditions:

  Room temperature

• Storage Conditions:

  4°C; Protect from light; Stable at room temperature or 37°C (98°F) for 7 days.

• Shelf Life:

  2 years