RIF1 rabbit pAb

• Gene ID:

  55183

• UniProt:

  Q5UIP0

• Cellular Locus:

  Nucleus. Chromosome. Chromosome, telomere. Cytoplasm, cytoskeleton, spindle. Following interaction with TP53BP1, recruited to sites of DNA damage, such as DSBs (By similarity). Exhibits ATM- and TP53BP1-dependent localization to uncapped or aberrant telomeres and to DNA double strand breaks (DSBs) (PubMed:15342490). Does not associate with normal telomere structures (PubMed:15342490, PubMed:15583028). Localizes to microtubules of the midzone of the mitotic spindle during anaphase, and to condensed chromosomes in telophase (PubMed:15583028)..

• Host:

  Rabbit

• Species Reactivity:

  Human, Mouse

• Immunogen:

  Synthesized peptide derived from human RIF1 AA range: 1428-1478

• Clonality:

  Polyclonal

• Validated Applications:

  WB

• Stability:

  1 year

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:1000-2000

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.