VEGF-CC, Human (116a.a, HEK293)

VEGF-CC, Human (116a.a, HEK293)

• UNSPSC Description: VEGF-C Protein, Human (116a.a, HEK293) functions in lymphangiogenesis, where it acts on lymphatic endothelial cells (LECs) primarily via its receptor VEGFR-3 promoting survival, growth and migration.
• Type: Recombinant Proteins
• Assay Protocol: https://www.medchemexpress.com/cytokines/vegf-c-protein-human-116a-a-hek293.html
• Purity: 95.00
• Smiles: AHYNTEILKS IDNEWRKTQC MPREVCIDVG KEFGVATNTF FKPPCVSVYR CGGCCNSEGL QCMNTSTSYL SKTLFEITVP LSQGPKPVTI SFANHTSCRC MSKLDVYRQV HSIIRR
• Molecular Weight: Approximately 15-24 kDa due to the glycosylation.
• References & Citations: [1]Joukov V, et al. A novel vascular endothelial growth factor, VEGF-C, is a ligand for the Flt4 (VEGFR-3) and KDR (VEGFR-2) receptor tyrosine kinases. EMBO J. 1996 Jan 15;15(2):290-98.|[2]Tammela T, et al. Blocking VEGFR-3 suppresses angiogenic sprouting and vascular network formation Nature. 2008 Jul 31;454(7204):656-60.|[3]Le Bras B, et al. VEGF-C is a trophic factor for neural progenitors in the vertebrate embryonic brain. Nat Neurosci. 2006 Mar;9(3):340-8.|[4]Machnik A, et al. Macrophages regulate salt-dependent volume and blood pressure by a vascular endothelial growth factor-C-dependent buffering mechanism. Nat Med. 2009 May;15(5):545-52.
• Shipping Conditions: Blue Ice
• Storage Conditions: Stored at -20°C for 2 years