AXC-715 (trihydrochloride)

• CAS Number:

  2479276-17-8

• UNSPSC Description:

  AXC-715 (T785) trihydrochloride is a TLR7/TLR8 dual agonist, extracted from patent WO2020168017 A1[1]. AXC-715 trihydrochloride, compound D from WO2020190734A1, can be used for synthesis of antibody-adjuvant immunoconjugates, comprising an antibody construct that binds programmed death-ligand 1 (PD-L1) linked to one or more adjuvants[2].

• Target Antigen:

  Toll-like Receptor (TLR)

• Type:

  Reference compound

• Related Pathways:

  Immunology/Inflammation

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/axc-715-trihydrochloride.html

• Smiles:

  NC1=NC2=C(C=CC=C2)C3=C1N=C(CCCC)N3CCCCN.Cl.Cl.Cl

• Molecular Weight:

  420.81

• References & Citations:

  [1]Sung-Ju Moon, et al. Compositions containing, methods and uses of antibody-tlr agonist conjugates. Patent WO2020168017A1.|[2]Shelley Erin ACKERMAN, et al. Immunoconjugates targeting pd-l1. Patent WO2020190734A1.

• Shipping Conditions:

  Room Temperature