Pyk2-IN-2

• CAS Number:

  1271418-15-5

• UNSPSC Description:

  Pyk2-IN-2 (compound 13j) is an inhibitor of Pyk2 with an IC50 of FAK kinase of 0.608 μM[1].

• Target Antigen:

  FAK; Pyk2

• Type:

  Reference compound

• Related Pathways:

  Protein Tyrosine Kinase/RTK

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  cancer

• Assay Protocol:

  https://www.medchemexpress.com/pyk2-in-2.html

• Purity:

  98.44

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  O=C(NC1=CC(C(C)(C)C)=NN1C2=CC=C(C)C=C2)NC3=NNC(C4=CC5=C(N=CC=C5)C=C4)=C3

• Molecular Weight:

  465.55

• References & Citations:

  [1]Bhattacharya SK, et al. Identification of novel series of pyrazole and indole-urea based DFG-out PYK2 inhibitors. Bioorg Med Chem Lett. 2012 Dec 15;22(24):7523-9.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, sealed storage, away from moisture and light)

• Clinical Information:

  No Development Reported