PROTAC ER Degrader-4
CAT:
804-HY-135309-05
Size:
100 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
PROTAC ER Degrader-4
- CAS Number: 2361114-15-8
- UNSPSC Description: PROTAC ER Degrader-4 is a von Hippel-Lindau-based PROATC estrogen receptor (ER) degrader, binding to ER with an IC50 of 0.8 nM. PROTAC ER Degrader-4 induces ER degradation in MCF-7 cells with an IC50 of 0.3 nM[1].
- Target Antigen: Estrogen Receptor/ERR; PROTACs
- Type: Reference compound
- Related Pathways: PROTAC;Vitamin D Related/Nuclear Receptor
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/protac-er-degrader-4.html
- Smiles: CC(C)(F)CN1[C@H](C2=C(C=C(OCCOCCOCCOCC(N[C@@H](C(C)(C)C)C(N3[C@@H](C[C@@H](O)C3)C(N[C@H](C4=CC=C(C5=C(N=CS5)C)C=C4)C)=O)=O)=O)C=C2F)F)C6=C(C7=CC=CC=C7N6)C[C@H]1C
- Molecular Weight: 1005.19
- References & Citations: [1]Bin Yang, et al. Compounds and their use in treating cancer. WO2019123367A1.
- Shipping Conditions: Blue Ice