5,7,8-Trimethoxyflavone

• CAS Number:

  23050-38-6

• UNSPSC Description:

  5,7,8-Trimethoxyflavone (Norwogonin 5,7,8-trimethyl ether), isolated from Andrographis echioides, inhibits NO with an IC50 of 39.1 μM. 5,7,8-Trimethoxyflavone has anti-inflammatory activity[1].

• Target Antigen:

  NO Synthase

• Type:

  Natural Products

• Related Pathways:

  Immunology/Inflammation

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/5-7-8-trimethoxyflavone.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C1C=C(C2=CC=CC=C2)OC3=C(OC)C(OC)=CC(OC)=C13

• Molecular Weight:

  312.32

• References & Citations:

  [1]De-Yang Shen, et al. Chemical constituents from Andrographis echioides and their anti-inflammatory activity. Int J Mol Sci. 2012 Dec 27;14(1):496-514.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported