PROTAC GSPT1 degrader-2

• CAS Number:

  3024909-61-0

• UNSPSC Description:

  PROTAC GSPT1 degrader-2 (compound A) is a GSPT1 molecule glue with more than 95% degradation. GSPT1 degrader-8 inhibits cell viability in HL-60 cells with an IC50 of 10 nM[1].

• Target Antigen:

  Molecular Glues

• Type:

  Reference compound

• Related Pathways:

  PROTAC

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/protac-gspt1-degrader-2.html

• Smiles:

  O=C1NC(C(CC1)N2C(C3=CC=C(N4CCC(CC4)CN5C(N(CCC5)C6=CC(C7=C(Cl)C8=C(NC=C8CC)N=C7)=CC=C6)=O)C=C3C2=O)=O)=O

• Molecular Weight:

  708.21

• References & Citations:

  [1]Lichao FANG, et al. Gspt1 degraders, compositions comprising the degrader, and methods of using the same. French, WO2024073871A1. 2024-04-11

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported