MK-6240 Precursor

• CAS Number:

  1841444-11-8

• UNSPSC Description:

  MK-6240 Precursor (6e) is the synthetic precursor of (18)F]-MK-6240. (18)F]-MK-6240 is a tau positron emission tomography (PET) tracer for neurofibrillary tangles (NFTs), exhibiting high specificity and selectivity for binding to NFTs[1].

• Target Antigen:

  Others

• Type:

  Reference compound

• Related Pathways:

  Others

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/mk-6240-precursor.html

• Purity:

  99.54

• Solubility:

  DMSO : 25 mg/mL (ultrasonic)

• Smiles:

  O=C(OC(C)(C)C)N(C(OC(C)(C)C)=O)C1=C([N+]([O-])=O)C=CC2=C1C=C(N3C=CC4=C3C=NC=C4)N=C2

• Molecular Weight:

  505.52

• References & Citations:

  [1]6-(Fluoro-(18)F)-3-(1H-pyrrolo[2,3-c]pyridin-1-yl)isoquinolin-5-amine ([(18)F]-MK-6240): A Positron Emission Tomography (PET) Imaging Agent for Quantification of Neurofibrillary Tangles (NFTs). J Med Chem. 2016 May 26;59(10):4778-89.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Clinical Information:

  No Development Reported