Anti-HLA-DQ1/DQ3 Purified

Anti-HLA-DQ1/DQ3 Purified

• Background: The antibody HL-37 reacts with polymorphic determinant on human HLA-DQ1 and HLA-DQ3 molecules (recognized epitope was found on isolated beta chain of DQ1), but does not react with HLA-DQ2. DQ is the isotype of human MHC Class II molecules expressed on antigen-presenting cells (APC dendritic cells, B lymphocytes, monocytes, macrophages).
• Specifications: The antibody HL-37 reacts with extracellular polymorphic determinant on human HLA-DQ1 and HLA-DQ3 molecules (recognized epitope was found on isolated beta chain of DQ1), but does not react with HLA-DQ2. DQ is the isotype of human MHC Class II molecules expressed on antigen-presenting cells (APC dendritic cells, B lymphocytes, monocytes, macrophages).
• CAS Number: 9007-83-4
• Certification: RUO
• Host: Mouse
• Species Reactivity: Pig, Human
• Immunogen: Burkitt's lymphoma cell line Raji.
• Target Antigen: HLA-DQ1/DQ3
• Isotype: IgG3
• Clone: HL-37
• Applications: Flow cytometry: Recommended dilution: 1-4 μg/mL. Western blotting: non-reducing conditions.
• Validated Applications: FC, IP, WB
• Concentration: 1 mg/mL
• Format: Purified
• Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
• References & Citations: *Horejsi V, Nemec M, Angelisova P, Kristofova H, Gorga JC, Hilgert I: Characterization of seven new monoclonal antibodies against human DR, DR + DP and DQ1 + DQ3 antigens. Tissue Antigens. 1986 Nov28(5):288-97. , URL: https://www.ncbi.nlm.nih.gov/pubmed/2435017?dopt=A,
• Storage Conditions: Store at 2-8°C. Do not freeze.