Boc-C5-O-C5-O-C6-Cl

• CAS Number:

  1835705-52-6

• UNSPSC Description:

  Boc-C5-O-C5-O-C6-Cl (PROTAC Linker 2) is a PROTAC linker utilized to connect the respective tyrosine kinase inhibitor (TKI) to the E3 recruiting ligand.

• Target Antigen:

  PROTAC Linkers

• Type:

  Reference compound

• Related Pathways:

  PROTAC

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/PROTAC_Linker_2.html

• Purity:

  95.0

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(OC(C)(C)C)CCCCCOCCCCCOCCCCCCCl

• Molecular Weight:

  393.00

• References & Citations:

  [1]Lai AC, et al. Modular PROTAC Design for the Degradation of Oncogenic BCR-ABL. Angew Chem Int Ed Engl. 2016 Jan 11;55(2):807-10.|[2]ARYL SULFONOHYDRAZIDES. US 20170121321 A1.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Clinical Information:

  No Development Reported