CB2R/FAAH modulator-2

• CAS Number:

  2876918-68-0

• UNSPSC Description:

  CB2R/FAAH modulator-2 (compound 26) is a dual targeting modulator that acts as a CB2R agonist and FAAH inhibitor. The Ki values for CB2R/FAAH modulator-2 are 10.8 and 152.9 nM for CB2R and CB1R, respectively, and the IC50 value for FAAH is 6.2 μM. CB2R/FAAH modulator-2 can be used in studies related to cancer, deleterious inflammatory cascades occurring in neurodegenerative diseases, and COVID-19 infection[1].

• Target Antigen:

  Cannabinoid Receptor; FAAH

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein;Metabolic Enzyme/Protease;Neuronal Signaling

• Applications:

  COVID-19-anti-virus

• Field of Research:

  Cancer; Infection; Inflammation/Immunology; Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/cb2r-faah-modulator-2.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(C1=C(OCC2CCCCC2)C=CC=C1)NC3(C4)C[C@H]5C[C@@H]4C[C@H](C5)C3

• Molecular Weight:

  367.52

• References & Citations:

  [1]Francesca Intranuovo, et al. Development of N-(1-Adamantyl)benzamides as Novel Anti-Inflammatory Multitarget Agents Acting as Dual Modulators of the Cannabinoid CB2 Receptor and Fatty Acid Amide Hydrolase. J Med Chem. 2023 Jan 12;66(1):235-250.

• Shipping Conditions:

  Room Temperature

• Clinical Information:

  No Development Reported