PI-55

• CAS Number:

  1122579-42-3

• UNSPSC Description:

  PI-55 is a specific cytokinin receptor inhibitor. PI-55 is structurally related to 6-benzylaminopurine (BAP) and was shown to inhibit competitively BAP binding on Arabidopsis-specific receptors CRE1/AHK4 and AHK3. PI-55 inhibits cytokinins induced haustorium formation and increased parasite aggressiveness[1].

• Target Antigen:

  Parasite

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/pi-55.html

• Solubility:

  DMSO : 25 mg/mL (ultrasonic;warming;heat to 60°C)

• Smiles:

  OC1=C(CNC2=C3N=CNC3=NC=N2)C=CC=C1C

• Molecular Weight:

  255.28

• References & Citations:

  [1] Goyet V, et al. Haustorium initiation in the obligate parasitic plant Phelipanche ramosa involves a host-exudated cytokinin signal. J Exp Bot. 2017;68(20):5539-5552.

• Shipping Conditions:

  Room Temperature

• Clinical Information:

  No Development Reported