11β-HSD1-IN-1

• CAS Number:

  1203956-47-1

• UNSPSC Description:

  11β-HSD1-IN-1 is an inhibitor of 11β-hydroxydehydrogenase 1 (11β-HSD1), with an IC50 of 52 nM, and used for the treatment of pain.

• Target Antigen:

  11β-HSD

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/4H-1,2,4-Triazole,_3-_2-chloro-4-fluorophenyl_-4-methyl-5-[1-methyl-1-_2,4,6-trifluorophenoxy_ethyl]-.html

• Purity:

  99.80

• Solubility:

  10 mM in DMSO

• Smiles:

  CC(C1=NN=C(C2=CC=C(F)C=C2Cl)N1C)(C)OC3=C(F)C=C(F)C=C3F

• Molecular Weight:

  399.77

• References & Citations:

  [1]THERAPEUTIC AGENT FOR PAIN. WO2012033070A1

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Clinical Information:

  No Development Reported