Posaconazole (hydrate)
CAT:
804-HY-17373A
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No

Posaconazole (hydrate)
- CAS Number: 1198769-38-8
- UNSPSC Description: Posaconazole hydrate is a broad-spectrum, second generation, triazole compound with antifungal activity.
- Target Antigen: Fungal; Parasite
- Type: Reference compound
- Related Pathways: Anti-infection
- Applications: COVID-19-immunoregulation
- Field of Research: Infection; Cancer
- Assay Protocol: https://www.medchemexpress.com/posaconazole-hydrate.html
- Solubility: 10 mM in DMSO
- Smiles: FC1=CC=C([C@@]2(CN3C=NC=N3)C[C@H](COC4=CC=C(N5CCN(C6=CC=C(N7C=NN([C@@H](CC)[C@H](C)O)C7=O)C=C6)CC5)C=C4)CO2)C(F)=C1.O
- Molecular Weight: 718.79
- References & Citations: [1]Benaim G, et al. Amiodarone has intrinsic anti-Trypanosoma cruzi activity and acts synergistically with posaconazole. J Med Chem. 2006 Feb 9;49(3):892-9.|[2]Sabatelli F, et al. In vitro activities of posaconazole, fluconazole, itraconazole, voriconazole, and amphotericin B against a large collection of clinically important molds and yeasts. Antimicrob Agents Chemother. 2006 Jun;50(6):2009-15.|[3]Sansone-Parsons A, et al. Effect of a nutritional supplement on posaconazole pharmacokinetics following oral administration to healthy volunteers. Antimicrob Agents Chemother. 2006 May;50(5):1881-3.|[4]Veiga-Santos P, et al. Effects of amiodarone and posaconazole on the growth and ultrastructure of Trypanosoma cruzi. Int J Antimicrob Agents. 2012 Jul;40(1):61-71.|[5]Sun QN, et al. In vivo activity of posaconazole against Mucor spp. in an immunosuppressed-mouse model. Antimicrob Agents Chemother. 2002 Jul;46(7):2310-2.
- Shipping Conditions: Room temperature
- Clinical Information: Launched