Anti-Endostatin COL18A1 Antibody

Anti-Endostatin COL18A1 Antibody

• Background: COLA18A probably plays a major role in determining the retinal structure as well as in the closure of the neural tube.Endostatin potently inhibits endothelial cell proliferation and angiogenesis. May inhibit angiogenesis by binding to the heparan sulfate proteoglycans involved in growth factor signaling.
  
  Takayuki Furumatsu, J. Biochem. (Tokyo), Apr 2002; 131: 619 - 626.
  Sonja Stahl, Genes Cells, Sep 2005; 10: 929 - 939.
  NICOLAI MIOSGE, FASEB J, Oct 1999; 13: 1743.
  Nicholas J. MacDonald, J. Biol. Chem., Jun 2001; 276: 25190 - 25196.
• Description: Boster Bio Anti-Endostatin COL18A1 Antibody (Catalog # A01302). Tested in IHC applications. This antibody reacts with Human.
• Synonyms: Collagen alpha-1 (XVIII) chain;Endostatin;COL18A1;
• CAS Number: 9007-83-4
• Gene Name: COL18A1
• UniProt: P39060
• Host: Rabbit
• Reactivity: Human
• Immunogen: Synthesized peptide derived from human endostatin.
• Clonality: Polyclonal
• Applications: IHC
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Concentration: 1 mg/ml
• Form: Liquid
• Molecular Weight: 178188 MW
• Components: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Conditions: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.