DDR1/2 inhibitor-2

• CAS Number:

  2908756-11-4

• UNSPSC Description:

  DDR1/2 inhibitor-2 (Example 31) is a DDR1/DDR2 inhibitor, with IC50 values less than 100 nM. DDR1/2 inhibitor-2 can be used for research of cancer and fibrotic diseases[1].

• Target Antigen:

  Discoidin Domain Receptor

• Type:

  Reference compound

• Related Pathways:

  Protein Tyrosine Kinase/RTK

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer; Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/ddr1-2-inhibitor-2.html

• Solubility:

  DMSO : 16.67 mg/mL (ultrasonic;warming;heat to 60°C)

• Smiles:

  O=C(CN1C=CC2=C(C1=O)C(NC3=CC(C=NN4C)=C4C=C3)=CC=C2)NC5=CN=CC(C(F)(F)F)=C5

• Molecular Weight:

  492.45

• References & Citations:

  [1]Inder Bhamra, et al. Phenyl- and pyridopyrazole derivatives as inhibitors of ddr1. Patent. WO2023021278.

• Shipping Conditions:

  Room Temperature

• Clinical Information:

  No Development Reported