BRD4 degrader-4

• CAS Number:

  2851986-83-7

• UNSPSC Description:

  BRD4 degrader-4 (Compound 1-f) is a BRD4 degrader. BRD4 degrader-4 can be used for the research of cancer and other bromodomain related diseases[1].

• Target Antigen:

  Epigenetic Reader Domain

• Type:

  Reference compound

• Related Pathways:

  Epigenetics

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/protac-brd4-degrader-25.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CC1=C(C)SC2=C1C(C3=CC=C(C4=CC(NC(C5=C6N(C=CC=N6)N=C5)=O)=C(C=C4)F)C=C3)=N[C@@H](CC(N(C)C)=O)C7=NN=C(C)N27

• Molecular Weight:

  647.72

• References & Citations:

  [1]Bailey S, et al. Preparation of aminobiarylthienotriazolodiazepinylacetamide derivatives for use as BRD4 modulators. WO2022221786A2. 2022-10-20.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported