Recombinant Rat MOG (1-125)

• Short Description:

  Catalog Number: B2011482 (100 µg)_x000D_ Recombinant Rat MOG (1-125) is a high quality extracellular domain of rat MOG. This product has been used as molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request._x000D_ _x000D_

• Description:

  Recombinant Rat MOG (1-125)_x000D_ Catalog number: B2011482_x000D_ Lot number: Batch Dependent_x000D_ Expiration Date: Batch dependent_x000D_ Amount: 100 µg_x000D_ Molecular Weight or Concentration: 1 mg/mL_x000D_ Supplied as: Solution_x000D_ Applications: molecular tool for various biochemical applications_x000D_ Storage: -80 °C_x000D_ Keywords: Myelin Oligodendrocyte Glycoprotein_x000D_ Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ References:_x000D_ 1: Olsson T, Dahlman I, Wallström E, Weissert R, Piehl F. Genetics of rat neuroinflammation J Neuroimmunol. 2000 Jul 24;107(2):191-200._x000D_ 2: Bernard CC, Johns TG, Slavin A, Ichikawa M, Ewing C, Liu J, Bettadapura J. Myelin oligodendrocyte glycoprotein: a novel candidate autoantigen in multiple sclerosis J Mol Med (Berl). 1997 Feb;75(2):77-88._x000D_ 3: Marta CB, Oliver AR, Sweet RA, Pfeiffer SE, Ruddle NH. Pathogenic myelin oligodendrocyte glycoprotein antibodies recognize glycosylated epitopes and perturb oligodendrocyte physiology Proc Natl Acad Sci U S A. 2005 Sep 27;102(39):13992-7._x000D_ 4: de Graaf KL, Albert M, Weissert R. Autoantigen conformation influences both B- and T-cell responses and encephalitogenicity J Biol Chem. 2012 May 18;287(21):17206-17213._x000D_ 5: Adelmann M, Wood J, Benzel I, Fiori P, Lassmann H, Matthieu JM, Gardinier MV, Dornmair K, Linington C. The N-terminal domain of the myelin oligodendrocyte glycoprotein (MOG) induces acute demyelinating experimental autoimmune encephalomyelitis in the Lewis rat J Neuroimmunol. 1995 Dec;63(1):17-27._x000D_ 6: Magni G, Pedretti S, Audano M, Caruso D, Mitro N, Ceruti S. Glial cell activation and altered metabolic profile in the spinal-trigeminal axis in a rat model of multiple sclerosis associated with the development of trigeminal sensitization Brain Behav Immun. 2020 Oct;89:268-280._x000D_ 7: Galicia G, Lee DSW, Ramaglia V, Ward LA, Yam JY, Leung LYT, Li R, Handy M, Zhang J, Drohomyrecky PC, Lancaster E, Bar-Or A, Martin A, Gommerman JL. Isotype-Switched Autoantibodies Are Necessary To Facilitate Central Nervous System Autoimmune Disease in Aicda(-/-) and Ung(-/-) Mice J Immunol. 2018 Aug 15;201(4):1119-1130._x000D_ 8: Gori F, Mulinacci B, Massai L, Avolio C, Caragnano M, Peroni E, Lori S, Chelli M, Papini AM, Rovero P, Lolli F. IgG and IgM antibodies to the refolded MOG(1-125) extracellular domain in humans J Neuroimmunol. 2011 Apr;233(1-2):216-20._x000D_ 9: Dahm L, Ott C, Steiner J, Stepniak B, Teegen B, Saschenbrecker S, Hammer C, Borowski K, Begemann M, Lemke S, Rentzsch K, Probst C, Martens H, Wienands J, Spalletta G, Weissenborn K, Stöcker W, Ehrenreich H. Seroprevalence of autoantibodies against brain antigens in health and disease Ann Neurol. 2014 Jul;76(1):82-94._x000D_ 10: El-Deeb OS, Ghanem HB, El-Esawy RO, Sadek MT. The modulatory effects of luteolin on cyclic AMP/Ciliary neurotrophic factor signaling pathway in experimentally induced autoimmune encephalomyelitis IUBMB Life. 2019 Sep;71(9):1401-1408. _x000D_ _x000D_ Products Related to Recombinant Rat MOG (1-125) can be found at Proteins

• CAS Number:

  9000-83-3

• Weight:

  0.15

• Length:

  2

• Width:

  0.5

• Height :

  0.5