Uroplakin 1B Recombinant Antibody / UPK1B

• Description:

  The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is found in the asymmetrical unit membrane (AUM) where it can form a complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions.UPK1B is expressed by terminally differentiated urothelial cells.

• CAS Number:

  9000-83-3

• UniProt:

  O75841

• Host:

  Rabbit

• Immunogen:

  A recombinant fragment (within amino acids 109-229) of human Uroplakin 1B/UPK1B protein was used as the immunogen for the recombinant Uroplakin 1B antibody.

• Clonality:

  Monoclonal

• Isotype:

  IgG κ

• Type:

  Recombinant

• Applications:

  IHC-P

• Format:

  Purified

• Buffer:

  0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

• Reconstitution:

  Aliquot the recombinant Uroplakin 1B antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

• Limitations:

  This recombinant Uroplakin 1B antibody is available for research use only.