Liproxstatin-1
CAT:
804-HY-12726-02
Size:
10 mM / 1 mL
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Liproxstatin-1
- CAS Number: 950455-15-9
- UNSPSC Description: Liproxstatin-1 is a potent ferroptosis inhibitor and inhibits ferroptotic cell death (IC50=22 nM)[1].
- Target Antigen: Ferroptosis
- Type: Reference compound
- Related Pathways: Apoptosis
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/Liproxstatin-1.html
- Purity: 99.90
- Solubility: DMSO : ≥ 31 mg/mL
- Smiles: ClC1=CC(CNC2=NC3=CC=CC=C3NC24CCNCC4)=CC=C1
- Molecular Weight: 340.85
- References & Citations: [1]Friedmann Angeli JP, et al. Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice. Nat Cell Biol. 2014 Dec;16(12):1180-91.|[2]Zilka O, et al. On the Mechanism of Cytoprotection by Ferrostatin-1 and Liproxstatin-1 and the Role of Lipid Peroxidation in Ferroptotic Cell Death. ACS Cent Sci. 2017 Mar 22;3(3):232-243
- Shipping Conditions: Room Temperature
- Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
- Clinical Information: No Development Reported