Meloxicam-d3-1
CAT:
804-HY-B0261S1
Size:
1 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No

Meloxicam-d3-1
- CAS Number: 1227358-55-5
- UNSPSC Description: Meloxicam-d3-1 is the deuterium labeled Meloxicam. Meloxicam is a non-steroidal antiinflammatory agent, inhibits COX activity, with IC50s of 0.49 µM and 36.6 µM for COX-2 and COX-1, respectively.
- Target Antigen: Apoptosis; Autophagy; COX
- Type: Isotope-Labeled Compounds
- Related Pathways: Apoptosis;Autophagy;Immunology/Inflammation
- Field of Research: Inflammation/Immunology; Cancer
- Purity: 98.0
- Solubility: 10 mM in DMSO
- Smiles: OC(C1=CC=CC=C12)=C(C(NC3=NC=C(S3)C([2H])([2H])[2H])=O)N(C)S2(=O)=O
- Molecular Weight: 354.42
- References & Citations: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. |[2]Lazer ES, et al. Effect of structural modification of enol-carboxamide-type nonsteroidal antiinflammatory drugs on COX-2/COX-1 selectivity. J Med Chem. 1997 Mar 14;40(6):980-9.|[3]Iturriaga MP, et al. Meloxicam decreases the migration and invasion of CF41.Mg canine mammary carcinoma cells. Oncol Lett. 2017 Aug;14(2):2198-2206.|[4]Fikry EM, et al. Rutin and meloxicam attenuate paw inflammation in mice: Affecting sorbitol dehydrogenase activity. J Biochem Mol Toxicol. 2018 Feb;32(2).
- Shipping Conditions: Room Temperature
- Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
- Clinical Information: No Development Reported