XIAP BIR2/BIR2-3 inhibitor-2

• CAS Number:

  1609384-83-9

• UNSPSC Description:

  XIAP BIR2/BIR2-3 inhibitor-2 is a dual inhibitor of BIR2 and BIR2-3 with IC 50s less than 1 nM. XIAP BIR2/BIR2-3 inhibitor-2 can used in study cancers[1].

• Target Antigen:

  IAP

• Type:

  Reference compound

• Related Pathways:

  Apoptosis

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/xiap-bir2-bir2-3-inhibitor-2.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(N1[C@@](C(N[C@H](C(N[C@H](C2=NN=NN2)CC3=CC=C(OCC4=CN5N=N4)C=C3)=O)CC6=CC(C=CC=C7)=C7C=C6)=O)([H])[C@](CC1)([H])N8C=C(COC9=CC=C(C[C@H](NC([C@@H](NC([C@]%10([H])[C@@]5([H])CCN%10C([C@H](C(C)(C)C)NC([C@H](C)NC)=O)=O)=O)CC%11=CC(C=CC=C%12)=C%12C=C%11)=O)C(O)=O)C=C9)N=N8)[C@H](C(C)(C)C)NC([C@H](C)NC)=O

• Molecular Weight:

  1529.75

• References & Citations:

  [1]Robert M. Borzilleri, et al. Macrocyclic compounds for inhibition of inhibitors of apoptosis. US20150284427A1. 2015-10-08.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported