SETD7-IN-1

• UNSPSC Description:

  SETD7-IN-1 (compound 7) is a PFI-2 (HY-18627) analogue. SETD7-IN-1 is a substrate and inhibitor of histone lysine methyltransferase SETD7, with an IC50 of 0.96 ± 0.10 µM[1].

• Target Antigen:

  Histone Methyltransferase

• Type:

  Reference compound

• Related Pathways:

  Epigenetics

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/setd7-in-1.html

• Solubility:

  10 mM in DMSO

• Smiles:

  FC1=CC(S(=O)(N[C@H](CC2=CC=CC=C2)C(NCCO)=O)=O)=CC3=C1CNCC3

• Molecular Weight:

  421.49

• References & Citations:

  [1]Porzberg M, et al. (R)-PFI-2 Analogues as Substrates and Inhibitors of Histone Lysine Methyltransferase SETD7. ChemMedChem. 2023 Oct 23:e202300457.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported