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5'-O-(4,4'-Dimethoxytrityl)-2'-O-methyl-2-thiouridine

CAT:
804-HY-154223
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  • Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
  • Dry Ice Shipment: No
5'-O-(4,4'-Dimethoxytrityl)-2'-O-methyl-2-thiouridine - image 1

5'-O-(4,4'-Dimethoxytrityl)-2'-O-methyl-2-thiouridine

  • CAS Number: 302918-83-8
  • UNSPSC Description: 5'-O-(4,4'-Dimethoxytrityl)-2'-O-methyl-2-thiouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
  • Target Antigen: Nucleoside Antimetabolite/Analog
  • Type: Oligonucleotides
  • Related Pathways: Cell Cycle/DNA Damage
  • Applications: Cancer-programmed cell death
  • Field of Research: Cancer
  • Assay Protocol: https://www.medchemexpress.com/5-o-4-4-dimethoxytrityl-2-o-methyl-2-thiouridine.html
  • Solubility: 10 mM in DMSO
  • Smiles: O[C@H]1[C@@H](OC)[C@H](N2C(NC(C=C2)=O)=S)O[C@@H]1COC(C3=CC=CC=C3)(C4=CC=C(OC)C=C4)C5=CC=C(OC)C=C5
  • Molecular Weight: 576.66
  • References & Citations: [1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.
  • Shipping Conditions: Room temperature
  • Clinical Information: No Development Reported

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