AChE/HDAC-IN-1
CAT:
804-HY-147962
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
AChE/HDAC-IN-1
- CAS Number: 2414053-06-6
- UNSPSC Description: COX-2-IN-23 (compound A10) is a potent both AChE and HDAC inhibitor with IC50 values of 0.12 and 0.23 nM. COX-2-IN-23 exhibits antioxidant activity and metal chelating properties. COX-2-IN-23 can be used in alzheimer's disease research[1].
- Target Antigen: Cholinesterase (ChE); HDAC
- Type: Reference compound
- Related Pathways: Cell Cycle/DNA Damage;Epigenetics;Neuronal Signaling
- Applications: Neuroscience-Neurodegeneration
- Field of Research: Neurological Disease
- Assay Protocol: https://www.medchemexpress.com/ache-hdac-in-1.html
- Solubility: 10 mM in DMSO
- Smiles: O=C(NCCCNC1=C(CCCC2)C2=NC3=CC(Cl)=CC=C31)C4=CC=C(/C=C/C(NO)=O)C=C4
- Molecular Weight: 478.97
- References & Citations: [1]Xu A, et al. Tacrine-hydroxamate derivatives as multitarget-directed ligands for the treatment of Alzheimer's disease: Design, synthesis, and biological evaluation. Bioorg Chem. 2020 May;98:103721.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported