NaPi2b-IN-3

• CAS Number:

  2227443-66-3

• UNSPSC Description:

  NaPi2b-IN-3 (compound 5) is a potent sodium-dependent transport protein 2b (SLC34A2, NaPi2b) inhibitor with IC50s of 71 nM and 28 nM for human NaPi2b and rat NaPi2b, respectively. NaPi2b-IN-3 can be used for researching hyperphosphatemia[1].

• Target Antigen:

  Others

• Type:

  Reference compound

• Related Pathways:

  Others

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/napi2b-in-3.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CCC(N(CC1=CC(C(NC2=C(C3=C(N2)C=CC=C3)C(NC4=CC=C(C=C4)CCCC5=CC=C(C=C5)C(O)=O)=O)=O)=CC=C1)CCN(C(CCC(O)=O)=O)C)CC

• Molecular Weight:

  773.92

• References & Citations:

  [1]Ushiki Y, et al. Design, synthesis and biological evaluation of novel indole derivatives as gut-selective NaPi2b inhibitors. Bioorg Med Chem. 2022;66:116783.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported