CYP3A4 enzyme-IN-1

• CAS Number:

  2531281-25-9

• UNSPSC Description:

  CYP3A4 enzyme-IN-1 (compound 59) is a potent antibacterial agent, with a MIC of 1 μg/mL for MRSA. CYP3A4 enzyme-IN-1 exhibits low to moderate inhibitory effects on CYP1A2, CYP2E1, CYP2D6, and CYP3A4 enzymes[1].

• Target Antigen:

  Bacterial; Cytochrome P450

• Type:

  Reference compound

• Related Pathways:

  Anti-infection;Metabolic Enzyme/Protease

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/cyp3a4-enzyme-in-1.html

• Solubility:

  10 mM in DMSO

• Smiles:

  C[C@@H]1[C@]23[C@](C(CC3)=O)([H])[C@]([C@@H](C[C@](C)([C@H]1O)C=C)OC(CN4CCN(CC4)C(CN5C=C(N=N5)CN6CCN(C7=CC=C(C=C7)[N+]([O-])=O)CC6)=O)=O)([C@@H](CC2)C)C

• Molecular Weight:

  774.95

• References & Citations:

  [1]Zhang GY, et, al. Design, synthesis and biological evaluation of novel pleuromutilin derivatives containing piperazine and 1,2,3-triazole linker. Bioorg Chem. 2020 Dec;105:104398.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported