Transthyretin-IN-1

• UNSPSC Description:

  Transthyretin-IN-1 (Compound 1d) is a transthyretin (TTR) fibril formation inhibitor. Transthyretin-IN-1 can be used for Alzheimer’s disease research[1].

• Target Antigen:

  Transthyretin (TTR)

• Type:

  Reference compound

• Related Pathways:

  Neuronal Signaling

• Applications:

  Neuroscience-Neurodegeneration

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/transthyretin-in-1.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(O)CCO/N=C/C1=CC(Br)=CC(Br)=C1O

• Molecular Weight:

  366.99

• References & Citations:

  [1]Ciccone L, et al. Monoaryl derivatives as transthyretin fibril formation inhibitors: Design, synthesis, biological evaluation and structural analysis. Bioorg Med Chem. 2020 Sep 15;28(18):115673.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported