m7GpppGmpG

• CAS Number:

  1258049-00-1

• UNSPSC Description:

  m7GpppGmpG is a trinucleotide 5′ cap analog with the capping efficiencies for the obtained RNAs of 86%[1].

• Target Antigen:

  DNA/RNA Synthesis

• Type:

  Oligonucleotides

• Related Pathways:

  Cell Cycle/DNA Damage

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/m7gpppgmpg.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=P(O)(OC[C@@H]1[C@@H](OP(O)(OC[C@H]2O[C@@H](N3C(NC(N)=NC4=O)=C4N=C3)[C@H](O)[C@@H]2O)=O)[C@@H](OC)[C@H](N5C(NC(N)=NC6=O)=C6N=C5)O1)OP(OP(OC[C@H]7O[C@@H](N8C(NC(N)=N9)=C([N+](C)=C8)C9=O)[C@H](O)[C@@H]7O)([O-])=O)(O)=O

• Molecular Weight:

  1161.66

• References & Citations:

  [1]Sikorski PJ, et, al. The identity and methylation status of the first transcribed nucleotide in eukaryotic mRNA 5' cap modulates protein expression in living cells. Nucleic Acids Res. 2020 Feb 28;48(4):1607-1626.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported