EB-0150
CAT:
804-HY-145273
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No

EB-0150
- CAS Number: 2832824-40-3
- UNSPSC Description: EB-0150 is a potent inhibitor of ER α-glucosidases (α-Glu) Iand II with IC50s of 0.73 and 0.0337 μM, respectively. EB-0150 is a N-substituted derivative of valiolamine with broad-spectrum antiviral. EB-0150 has the potential for the reseach of broad-spectrum agent against the existing and emerging viruses[1]. EB-0150 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- Target Antigen: Glycosidase
- Type: Reference compound
- Related Pathways: Metabolic Enzyme/Protease
- Applications: COVID-19-anti-virus
- Field of Research: Infection
- Assay Protocol: https://www.medchemexpress.com/eb-0150.html
- Solubility: 10 mM in DMSO
- Smiles: O[C@@H]1[C@](O)(C[C@@H]([C@@H]([C@H]1O)O)NCCCCCCNC2=C(C=C(C=C2)N=[N+]=[N-])[N+]([O-])=O)CO
- Molecular Weight: 454.48
- References & Citations: [1]Karade SS, et al. N-Substituted Valiolamine Derivatives as Potent Inhibitors of Endoplasmic Reticulum α-Glucosidases I and II with Antiviral Activity. J Med Chem. 2021;64(24):18010-18024.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported