TRPC5-IN-1

• CAS Number:

  2265215-18-5

• UNSPSC Description:

  TRPC5-IN-1 (Compound 6j) is a selective TRPC5 inhibitor with 50.5 % Inhibition for TRPC5 at 3 μM. TRPC5-IN-1 can be used for the research of chronic kidney disease (CKD)[1].

• Target Antigen:

  TRP Channel

• Type:

  Reference compound

• Related Pathways:

  Membrane Transporter/Ion Channel;Neuronal Signaling

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/trpc5-in-1.html

• Solubility:

  10 mM in DMSO

• Smiles:

  N#CC1=CC=C(CN2C(NCC3=CC=CO3)=NC4=C2C=CC=C4)C=C1

• Molecular Weight:

  328.37

• References & Citations:

  [1]Sharma SH, et al. Design, synthesis and characterization of novel N-heterocyclic-1-benzyl-1H-benzo[d]imidazole-2-amines as selective TRPC5 inhibitors leading to the identification of the selective compound, AC1903. Bioorg Med Chem Lett. 2019 Jan 15;29(2):155-159.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported