CDK7-IN-12

• CAS Number:

  2750638-94-7

• UNSPSC Description:

  CDK7-IN-12 is a potent inhibitor of CDK7. CDK7-IN-12 plays a key role in transcriptional regulation and cell cycle regulation. CDK7-IN-12 effectively inhibit malignant tumor proliferation in vitro and in vivo. CDK7-IN-12 has the potential for the research of cancer disease (extracted from patent WO2021249417A1, compound 43)[1].

• Target Antigen:

  CDK

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/cdk7-in-12.html

• Solubility:

  10 mM in DMSO

• Smiles:

  FC(C1=C(C2=CNC3=C2C=CC=C3)N=C(N[C@@H]4CNCCC4)C5=NC=CN51)(F)F

• Molecular Weight:

  400.40

• References & Citations:

  [1]Jing Wang, et al. Heterocyclic compounds and their derivatives. Patent WO2021249417A1.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported