TP-16

• CAS Number:

  2332972-26-4

• UNSPSC Description:

  TP-16 is a novel and selective EP4 antagonist with an IC50 of 2.1 nM.

• Target Antigen:

  Prostaglandin Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/tp-16.html

• Solubility:

  10 mM in DMSO

• Smiles:

  C[C@@H](C1=CC=C(C=C1)C(O)=O)NC(C2=C(CC3=CC=C(C=C3)F)SC4=C2CCOC4)=O

• Molecular Weight:

  439.50

• References & Citations:

  [1]Lu W, et al. Reprogramming immunosuppressive myeloid cells facilitates immunotherapy for colorectal cancer. EMBO Mol Med. 2021 Jan 11;13(1):e12798.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported