DBCO-NHCO-PEG12-biotin

DBCO-NHCO-PEG12-biotin

• CAS Number: 2621391-31-7
• UNSPSC Description: DBCO-NHCO-PEG12-biotin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. DBCO-NHCO-PEG12-biotin is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
• Target Antigen: PROTAC Linkers
• Type: Dye Reagents
• Related Pathways: PROTAC
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/dbco-nhco-peg12-biotin.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(CCNC(CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(CCCC[C@@H]1SC[C@]([C@]1([H])N2)([H])NC2=O)=O)=O)N3C4=CC=CC=C4C#CC5=CC=CC=C5C3
• Molecular Weight: 1102.34
• References & Citations: [1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported