Angiotensin I Converting Enzyme (ACE)/CD143

• Gene Name:

  [ACE]

• NCBI Gene ID:

  1636

• Reactivity:

  Human

• Storage Conditions:

  Antibody with azide: store at 2 to 8 degree C.
  Antibody without azide: store at -20 to -80 degree C.
  Antibody is stable for 24 months. Non-hazardous. No MSDS required.

• Specificity:

  This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Two most abundant alternatively spliced variants of this gene encode two isozymes - the somatic form and the testicular form that are equally active. Multiple additional alternatively spliced variants have been identified but their full length nature has not been determined.

• Other Gene Names:

  [ACE; ACE; DCP; ACE1; DCP1; CD143; DCP; DCP1; ACE]

• Short Name:

  [Angiotensin]

• Other Product Names:

  [angiotensin I converting enzyme, partial; Angiotensin-converting enzyme; angiotensin-converting enzyme; angiotensin I converting enzyme; Dipeptidyl carboxypeptidase I; Kininase II]

• NCBI GI Number:

  76057114

• NCBI Accession Number:

  ABA39229.1

• Uniprot Accession Number:

  P12821