CD43 (T-Cell Marker)

• Gene Name:

  [SPN]

• NCBI Gene ID:

  6693

• Reactivity:

  Human

• Storage Conditions:

  Antibody with azide: store at 2 to 8 degree C.
  Antibody without azide: store at -20 to -80 degree C.
  Antibody is stable for 24 months. Non-hazardous. No MSDS required.

• Specificity:

  It recognizes a cell surface glycoprotein of 95/115/135kDa (depending upon the extent of glycosylation), identified as CD43. 70-90% of T-cell lymphomas and from 22-37% of B-cell lymphomas express CD43. No reactivity has been observed with reactive B-cells. So a B-lineage population that co-expresses CD43 is highly likely to be a malignant lymphoma, especially a low-grade lymphoma, rather than a reactive B-cell population. When CD43 antibody is used in combination with anti-CD20, effective immunophenotyping of the lymphomas in formalin-fixed tissues can be obtained. Co-staining of a lymphoid infiltrate with anti-CD20 and anti-CD43 argues against a reactive process and favors a identification of lymphoma.

• Other Gene Names:

  [SPN; SPN; LSN; CD43; GALGP; GPL115; CD43; GALGP]

• Short Name:

  [CD43]

• Other Product Names:

  [leukosialin; Leukosialin; leukosialin; sialophorin; Galactoglycoprotein; GALGP; Leukocyte sialoglycoprotein; Sialophorin; CD_antigen: CD43]

• NCBI GI Number:

  71979937

• NCBI Accession Number:

  NP_001025459.1

• NCBI GB Accession Number:

  NP_001025459.1

• Uniprot Accession Number:

  P16150