CD4 (T-Helper/Inducer Cell Marker)

• Gene Name:

  [CD4]

• NCBI Gene ID:

  920

• Reactivity:

  Human, Monkey

• Storage Conditions:

  Antibody with azide: store at 2 to 8 degree C.
  Antibody without azide: store at -20 to -80 degree C.
  Antibody is stable for 24 months. Non-hazardous. No MSDS required.

• Specificity:

  Recognizes a protein of 55kDa, identified as CD4. It is a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigens and is also a receptor for the human immunodeficiency virus. This protein is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.

• Other Gene Names:

  [CD4; CD4; CD4mut]

• Short Name:

  [CD4]

• Other Product Names:

  [T-cell surface glycoprotein CD4 isoform 1; T-cell surface glycoprotein CD4; T-cell surface glycoprotein CD4; CD4 molecule; T-cell surface antigen T4/Leu-3]

• NCBI GI Number:

  10835167

• NCBI Accession Number:

  NP_000607.1

• NCBI GB Accession Number:

  NP_000607.1

• Uniprot Accession Number:

  P01730