Vimentin (Mesenchymal Cell Marker)

• Gene Name:

  [VIM]

• NCBI Gene ID:

  7431

• Reactivity:

  Human
  Does not react with Mouse or Rat.

• Storage Conditions:

  Antibody with azide: store at 2 to 8 degree C.
  Antibody without azide: store at -20 to -80 degree C.
  Antibody is stable for 24 months. Non-hazardous. No MSDS required.

• Specificity:

  This MAb reacts with a 58kDa protein identified as vimentin. It shows no cross-reaction with other closely related intermediate filament proteins (IFP s) such as desmin, keratin, neurofilament, and glial fibrillary acid protein.Anti-vimentin alone is of limited value as a tool; however, when used in panels with other antibodies, it is useful for the sub-classification of a given tumor. Expression of vimentin, when used in conjunction with anti-keratin, is helpful when distinguishing melanomas from undifferentiated carcinomas and large cell lymphomas. All melanomas and Schwannomas react strongly with anti-vimentin. It labels a variety of mesenchymal cells, including melanocytes, lymphocytes, endothelial cells, and fibroblasts. Non-reactivity of anti-vimentin is often considered more useful than its positive reactivity, since there are a few tumors that do not contain vimentin, e.g. hepatoma and seminoma. Anti-vimentin is also useful as a tissue process control reagent.

• Other Gene Names:

  [VIM; VIM]

• Short Name:

  [Vimentin]

• Other Product Names:

  [vimentin; Vimentin; vimentin; vimentin]

• NCBI GI Number:

  62414289

• NCBI Accession Number:

  NP_003371.2

• NCBI GB Accession Number:

  NP_003371.2

• Uniprot Accession Number:

  P08670