FABP5 (Marker of Metastatic Potential in Colorectal Cancer)

• Gene Name:

  [FABP5]

• NCBI Gene ID:

  2171

• Reactivity:

  Human

• Storage Conditions:

  Antibody with azide: store at 2 to 8 degree C.
  Antibody without azide: store at -20 to -80 degree C.
  Antibody is stable for 24 months. Non-hazardous. No MSDS required.

• Specificity:

  This gene encodes the fatty acid binding protein found in epidermal cells, and was first identified as being upregulated in psoriasis tissue. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABPs may play roles in fatty acid uptake, transport, and metabolism. Polymorphisms in this gene are associated with type 2 diabetes. The human genome contains many pseudogenes similar to this locus. FABP5 is also associated with poor survival in triple-negative breast cancer. Additionally, FABP5 gene is upregulated in colorectal cancer cells compared to normal colon cells in a manner that correlates with disease stage and that FABP5 significantly promotes colorectal cancer cell growth and metastatic potential.

• Other Gene Names:

  [FABP5; FABP5; EFABP; KFABP; E-FABP; PAFABP; PA-FABP; E-FABP; PA-FABP]

• Short Name:

  [FABP5]

• Other Product Names:

  [Fatty acid-binding protein 5; Fatty acid-binding protein, epidermal; fatty acid-binding protein 5; fatty acid binding protein 5; Epidermal-type fatty acid-binding protein; E-FABP; Fatty acid-binding protein 5; Psoriasis-associated fatty acid-binding protein homolog]

• NCBI GI Number:

  232081

• NCBI Accession Number:

  Q01469.3

• Uniprot Accession Number:

  Q01469